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This is quite the unique strain I must say. The smoke was a bit harsh, but the effects were very different than from what I've experienced in other strains, and especially for an Indica dominant strain. Querkle is without a doubt the most uplifting strain I've experienced, but without being overbearing, sedating or couch locking. It simply just brings up your happiness levels, I found my thoughts automatically optimistic, and creativity also spiked during its peak. It almost works more like a sativa strain does, as far as cerebrally, but with the duration of indica strains. That makes it one hell of a strain and well worth a try. One interesting side effect I experienced with this particular strain was dizziness, I noted an acute and most definite wobble in my equilibrium, but only from sitting to standing or crouching to standing positions. This was consistent with every use of this strain (as was the uplifting effects), so I do not attribute it to malnutrition, dehydration, tiredness or other conditions which may cause dizziness. Dry mouth and dry eyes didn't seem to be present much if at all, but that was just my experience anyway when I smoked it. I would highly, most definitely recommend this strain to anyone suffering depression, PTSD, bipolar disorder, borderline personality disorder, anxiety, PMS, moodiness, irritability and anger suppression. The optimism I received from this strain makes antidepressants seem like mere sugar pills. If you're lucky enough to own a large gorgeous bong/water pipe, one, maybe two solid tokes should be an optimism bomb of epic proportions.