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I have been using this strain predominantly for arthritis pain, post-cancer, anxiety and sleep. I have the great fortune to have a supplier who grows only hydroponic, organic meds. Charlie Sheen OG is the best of many strains I have used for all the above symptoms. I also find that, if I want to sleep, I am out... but if I want to get work done, I focus and I am a MACHINE!!! The buds are super dense and sticky, and the smell is amazing... and amazingly strong! I have started to make sure I'm seated whenever medicating, as nearly every hit comes with a head and/or body rush. I learned the hard way when I got the first shiner of my life after face planting from a sting hit. Seriously. Overall, the best. Two thumbs up!!!