Marijuana strains that may help migraines

Few things can floor you and disrupt your day faster than a migraine. Recognized as one of the most common forms of headache disorders, medical experts define migraines as a pervasive neurological disease with a range of nasty symptoms, from throbbing temples to nausea and extreme sensitivity to sound and light stimuli.

Beyond being exceptionally painful, migraines also tend to stick around, often lasting for days and, in extreme cases, even weeks at a time. Unfortunately, no universal solution exists for treating migraine symptoms. Though some have found relief in the form of prescription drugs, the unwanted side effects associated with many of these medications can outweigh their intended benefits for a significant number of patients. Furthermore, only about half of migraine sufferers have seen a doctor about their condition. For this reason, some have turned to cannabis as a therapeutic aid for treating migraines. By seeking out strains rich with certain terpenes and cannabinoids—two essential compounds that define each strain’s unique characteristics—studies have found that patients may be able to tame primary migraine symptoms, like pain and nausea.

Read on to discover the science underpinning weed’s efficacy as a migraine treatment, a summary of its potential benefits to patients, and Leafly’s recommendations for both the best and strongest strains that can provide relief. 

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Frequently asked questions

As science continues to investigate the relationship between cannabis and migraines, the results look promising. Several studies in recent years have found positive correlations between cannabis consumption and relief from migraine symptoms. But as with all aspects of cannabis, further study is needed.

In 2018, for example, researchers found that THC could provide analgesic pain relief at 20 times the level of anti-inflammatories like aspirin. The following year, a separate, limited review focused on 316 patients found that 88.3% of them reported improvement in their migraine symptoms following the use of medicinal cannabis.

The consensus, at least for now, points to THC’s ability to restore normative function to the endocannabinoid system as a key component of the process. Additionally, migraine sufferers can benefit from CBD, a non-psychoactive and anti-inflammatory cannabinoid, and can find even further possible relief by targeting certain terpenes as well.

To put together the best possible list of strains for migraine sufferers to seek out, we referenced Leafly user reviews, checked out sales figures, and double-checked with our experts on staff to serve up five surefire winners.

  1. Platinum Zkittlez

    At the top of our list is a balanced hybrid featuring plenty of beta-caryophyllene, a terpene reputed for being especially effective in treating migraine symptoms. Additionally, Leafly users also applaud Platinum Zkittlez for its reliable ability to make them feel giggly, uplifted, and euphoric while pleasing the palate with a taste that blends notes of tropical fruit and spice.

  2. Cactus Cooler

    Looking for cerebral relief and a buzz of euphoria to counter a migraine? Take a long gulp of Cactus Cooler, a sativa-dominant hybrid popular with Leafly users bred from Blue Dream and OG Kush. That would explain its refreshing flavors, featuring a burst of lemon and sweet wildflowers

  3. Blackwater

    For migraine relief that can double as a sleep aid, dip a toe in the calming currents of Blackwater. Made by crossing Mendo Purps with San Fernando Valley OG Kush, this strain starts mellow, then spreads into a classic, full-body high that alleviates pain and stimulates stalled appetites. To top it off, Blackwater features an alluring grape aroma with notes of pine and lemon.

  4. Platinum Lemon Cherry Gelato

    Some migraine patients may find balanced hybrids work best; If that’s the case, Platinum Lemon Cherry Gelato is an ideal candidate. Beyond getting you high in a hurry—this is a strain that regularly averages 27-30% THC—Platinum Lemon Cherry Gelato can spark creativity, help you feel focused, and alleviate symptoms like headaches, depression, and stress.

  5. Real OG

    Real OG is classified as an indica-leaning strain. As a phenotype of classic OG Kush, Real OG is a potent, stimulating option for migraine patients by helping address symptoms like pain, insomnia, and exhaustion. Minty, spicy, and beloved by Leafly users, Real OG is a great strain to try for some cosmically chronic mental cleansing.

Cannabis strains exist on a vast spectrum of potency and ratios, from the non-psychoactive effects of CBD to face-melting dabs. The best way to determine a strain’s efficacy is to look at its terpenes, concentrations of various cannabinoids, and genetics. That said, we’ve compiled five of the strongest options geared at getting relief from migraines that hit fast and last long.

  1. Roze Gold Runtz

    Bred by CopyCat Genetics, Rose Gold Runtz is a hybrid strain known for its aromas and flavors of blueberry, rose, and fruit. In addition to making consumers feel euphoric and creative, Leafly users report turning to Rose Gold Runtz to help treat ailments like anxiety, depression, and headaches. Featuring an eye-popping 32% THC, this strain is the dictionary definition of a classic heavy hitter.

  2. Super Boof

    This zingy hybrid is made by crossing Black Cherry Punch and Tropicana Cookies, resulting in a strain that regularly tests at 28% THC. Known for being intensely relaxing and leaving consumers prone to giggle fits, Super Boof also packs plenty of myrcene — a preferred terpene among medical marijuana patients looking to treat migraine headache symptoms. You can expect divine notes of earth and cherry as well!

  3. White Papaya

    Get focused, uplifted—even aroused!—with star hybrid White Papaya. Made from a genetic cross between The White and Papaya, this strain is a great option for snuffing out migraines owing in no small part to its hefty potency (26% THC). Featuring a flavor profile that boasts notes of nuts, honey, and mango, White Papaya is also recognized as a valid aid to treat depression, fatigue, and cramping.

  4. La Bomba

    Sleep better, feel happier, and get pain-free—it’s all on the menu when you drop the needle on White PapayaLa Bomba. At 23% THC, this strain is both potent and pretty, with nugs that seem to burst with long amber hairs. Made by crossing Wedding Cake and Jet Fuel Gelato, La Bomba’s dominant terpene is limonene, providing a crisp, refreshing twist that you can both taste and feel.

  5. Josh D OG

    In 1991, Josh D and Matt “Bubba” Berger hit the lab to define a new era of OG cannabis culture. Josh D OG is a sterling example of their work. A triple cross of SFV OG x Triangle Kush x Hell’s Angels OG, this indica comes amplified with classic Kush flavor and 24% THC. Push snooze on a migraine with a sedative trip to calmer seas courtesy of some Josh D OG.

Smoking cannabis to treat migraines can offer a multitude of benefits. While it can’t cure headache disorders, weed can provide relief for many underlying symptoms, such as nausea and pain to facilitate better sleep. Studies have also found that cannabis may reduce migraine and headache severity by as much as 50%.

Strains that can provide a body high are known to be calming and relaxing, which can help with migraine symptoms. These type of relaxing strains can be found in both indica and sativa form.

Yes, in medically legalized states migraines may qualify you for a medical marijuana card.



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