We use cookies for certain features and to improve your experience. See our Cookie Policy and Privacy Policy to learn more

Leafly

Shop legal, local weed.

Open
advertise on Leafly
ShopDeliveryDispensariesDealsStrainsBrandsProductsCBDDoctorsCannabis 101Social impact
  • Sign in
  • Create account
  • Strains
  • Shop
  • Shop
  • Delivery
  • Deals
  • Dispensaries
  • CBD Stores
  • Brands
  • Products
  • Learn
  • Cannabis 101
  • News
  • Leafly Learn
  • Science of cannabis
  • Doctors
  • Social impact
  • Lab partners
  • Download the Leafly App
  • Advertise on Leafly
    • Leafly.comUSA flag
    • Leafly.caCanadian flag
    • Leafly.deGerman flag
  • Help
  • News
  • Lifestyle
  • Strains & products
  • Industry
  • Growing
  • Health
  • Science & tech
  • Leafly USA
  • Podcasts
  • Learn
Health

Science chat: Dissecting the new study on cannabis abuse and depression

David DownsPublished on July 14, 2023
(Gillian Levine for Leafly)
(Gillian Levine for Leafly)

Millions of people worldwide use cannabis to treat mood issues as legalization continues to spread.

People smoke pot to reduce anxiety, and depression, and many have found lifesaving relief. Considering its status as an effective neuro-modulator, it’s no surprise that people experiencing nervous system dysregulation seek out cannabis for its many effects. But cannabis’ ability to help also exists alongside its potential for misuse, and potential to cause harm.

Last week, the Wall Street Journal ran a column under the headline “Cannabis is linked to mental illness” that referenced a paper published this May in JAMA Psychiatry: The study concluded that patients diagnosed with cannabis use disorder (CUD) had a higher than average likelihood of a subsequent diagnosis of depression or bipolar disorder.

The study authors acknowledge, however, that correlation may not equal causation. And the study has had to contend with what’s called ‘detection bias’ in its focus population.

Leafly’s Director of Science and Innovation, Nick Jikomes Ph.D., as well as Leafly health and science correspondent Emily Earlenbaugh Ph.D., explain what the study says—and does not say—and offer some crucial missing context in the half-hour discussion, below. Click on the video to tune in.

Related articles

Is cannabis addictive? image
Image Not Found
Is cannabis addictive?
Emma Stone
THC tolerance: why t-breaks work so quickly image
Image Not Found
THC tolerance: why t-breaks work so quickly
Josh Kaplan
What Is Cannabinoid Hyperemesis Syndrome? image
Image Not Found
What Is Cannabinoid Hyperemesis Syndrome?
Bailey Rahn
How cannabis interacts with different antidepressants image
Image Not Found
How cannabis interacts with different antidepressants
Jeremy Kossen

Shop highly rated dispensaries near you

Showing you dispensaries near
See all dispensaries
  • Loading...
    Loading...Loading...
    Loading...
    Loading...Loading...
    Loading...Loading...
  • Loading...
    Loading...Loading...
    Loading...
    Loading...Loading...
    Loading...Loading...
  • Loading...
    Loading...Loading...
    Loading...
    Loading...Loading...
    Loading...Loading...
  • Loading...
    Loading...Loading...
    Loading...
    Loading...Loading...
    Loading...Loading...
  • See all dispensaries
See all dispensaries
addictionbipolar-disorderdepressioninterviewsresearchsciencevideo
David Downs
David Downs
Leafly Senior Editor David Downs is the former Cannabis Editor of the San Francisco Chronicle. He's appeared on The Today Show, and written for Scientific American, The New York Times, WIRED, Rolling Stone, The Onion A/V Club, High Times, and many more outlets. He is a 2023 judge for The Emerald Cup, and has covered weed since 2009.
View David Downs's articles

The latest in Health

  • Study finds legal cannabis promotes more physical activity image
    Study finds legal cannabis promotes more physical activity
    Emily Earlenbaugh
  • Big new study tracks cannabis replacing alcohol as a daily substance image
    Big new study tracks cannabis replacing alcohol as a daily substance
    Emily Earlenbaugh
  • Study: Early cannabis use in pregnancy doesn’t predict autism image
    Study: Early cannabis use in pregnancy doesn’t predict autism
    Emily Earlenbaugh
  • Study shows CBD can increase cannabis’ psychoactive effects image
    Study shows CBD can increase cannabis’ psychoactive effects
    Emily Earlenbaugh
Get good reads, local deals, and strain spotlights delivered right to your inbox.

By providing us with your email address, you agree to Leafly's Terms of Service and Privacy Policy.



Stay In Touch

Receive updates on new products, special offers, and industry news.

Something went wrong, please try again.

By providing us with your email address, you agree to Leafly’s Terms of Service and Privacy Policy.

Leafly mobile app
Get high for less.
Download the Leafly app.
Download Leafly: Marijuana Reviews on the App StoreDownload Leafly Marijuana Reviews on Google Play

Business Solutions
  • List your store
  • List your CBD store
  • List your brand
  • List your practice
  • Business log in

About Leafly
  • About us
  • Careers
  • Newsroom
  • Investor relations
  • Contact us
  • FAQs
  • Accessibility

Dispensaries in
  • Los Angeles
  • Seattle
  • Portland
  • San Francisco
  • Toronto
  • Detroit

Privacy & Terms
  • Terms of use
  • Commercial terms of use
  • Privacy policy
  • Do not sell my personal information

* Statements made on this website have not been evaluated by the U.S. Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Information provided by this website or this company is not a substitute for individual medical advice.


© 2025 Leafly, LLC
Leafly and the Leafly logo are registered trademarks of Leafly, LLC. All Rights Reserved.