Migraine pain 6; nausea 9 when I medicated round 2100 or so. Takes bout 10 min to start working. Pain/nausea gone. No anxiety/paranoia (an absolute must for me). Body high a lil heavier than I remembered but still very nice! Head high knocked my @## out, oops! Don't think my hubby was planning on that, lol! Still highly recommend for nighttime/bedtime use for pain/nausea/anxiety!