CBLA (cannabicyclolic acid)

CBLA (cannabicyclolic acid) is a rare non-intoxicating compound found in cannabis. CBLA is not an original cannabinoid present in living cannabis plants, but a photochemical product formed as a result of environmental changes that alter the chemical composition of CBCA (cannabichromenic acid). When CBCA is exposed to heat or UV light, it degrades and is converted into CBLA. 

“Although there’s still much to learn about cannabicyclolic acid, emerging research suggests it may hold anti-inflammatory benefits.”

What is CBLA?

CBLA is found in stored cannabis which has been harvested early in its vegetative phase. It is synthesized from CBCA that has been exposed to UV light. The cannabinoid was first isolated by Shoyama, Oku, and Yamauchi in 1972, and according to the researchers, CBLA is not an original cannabinoid and should be categorized as an artificial product. 

Scientists currently have very little knowledge of CBLA, as it occurs in such low concentrations in cannabis. Research thus far does indicate that it is one of the more stable of cannabinoid acids when heated and is therefore more resistant to decarboxylation, the process by which cannabinoid acids become neutralized.

What are the benefits of CBLA?

Research exploring the therapeutic benefits of CBLA is still emerging. However, an impending patent suggests that this little-understood cannabis compound may hold potential as an anti-inflammatory compound. Increasing availability of CBLA from cannabis research companies suggests that studies into its applications will rise in coming years.