Strains & products

The world’s best cannabis seeds and clones to grow in ‘22

Published on January 26, 2022 · Last updated January 27, 2022
Catch me outside: Poddy Mouth is outdoor-optimized exotic Cakes crossed to Mints. (Courtesy Humboldt Seed Company )
Catch me outside: Poddy Mouth is outdoor-optimized exotic Cakes crossed to Mints. (Courtesy Humboldt Seed Company )

Good news, America: The nation’s army of weed growers in 2022 is going to fire up hundreds of metric tons of the most explosively tasty, time-stoppingly beautiful bud ever conceived on planet Earth.

Pot law liberalization has triggered a Golden Age of cannabis genetics—putting the loudest, most diverse ganja aromas and effects at the fingertips of gardeners big and small.

Major nurseries like Dark Heart Nursery in Oakland, CA, hold strain openings like fashion shows for the $18.3 billion legal industry. Los Angeles’ Seed Junky Genetics sold $1,000 clones of Super Runtz at The Emerald Cup on Dec. 11—200 of them. Champion breeders like Exotic Genetix have released $900 seed packs with NFT art direct to a rabid fanbase. It all sells out—powering more than 2,278 metric tons of legal US pot production annually.

Leafly’s annual “Best cannabis seeds to grow” synthesizes the quantitative with the qualitative: We pair strain search and menu trend data with breeder interviews, and event and store reporting; plus, we smoke hundreds of flavors, and grow a few pounds.

Go ahead and bury us. We’re seeds. (Courtesy Humboldt Seed Company)

Leafly News’ product picks are independent, and cannot be influenced by advertising. We’d love to fill our garden with these cultivars—the newest of the new and those re-mixed from the best of the present and past.

Get ready for all the Cakes, Mints, Cookies, Zkittlez, GMOs, and sativas you could spend a lifetime trimming. Whatever you smoke, now is the time to score some awesome seeds so you can pop them by spring, and have a pound laying around by Thanksgiving. This is Leafly’s Best cannabis seeds and clones to grow in ‘22.

Cake and Mints varietals for ‘22

Poddy Mouth

Cakes and mints for your backyard boogie: Poddy Mouth (Courtesy Humboldt Seed Co)
Cakes and mints for your backyard boogie: Poddy Mouth (Courtesy Humboldt Seed Co)

Best-selling Wedding Cake and Kush Mints cannabis families combine in Humboldt Seed Company’s filthy new Poddy Mouth, which is Humboldt Pound Cake x Mtn Top Mint.

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Emerald Cup-winning Ridgeline Farms named and endorsed this outdoor-optimized exotic. It can test beyond 30% THC while looking bonkers and smelling like soft, sweet, minty fuel. Sheesh!

For ’22, Humboldt Seed Co. has 85 regular, feminized, autoflower, or combo seed products, from 45 strains, in six states. They’re emblematic of how West Coast breeders own the strain game, thanks to decades of experience, plus baseball field-sized farms to test out thousands of new varieties at once.

There are so many tasty mint and cake strains out there this year.

See also: Mint a pound with Tiki Madman’s mints crosses like Apple Fritter Bx or Gelatti Mints, available online; in California, get clones of Purple City Genetics’ Gush Mints crosses, or Hendrx Nursery’s Candy Chrome No. 5 (Runtz x The Menthol).

Contemporary GSC and Gelato strains

Cherry Cosmo

Exotic Genetix Cherry Cosmo seeds will sell out this week. (via the Exotic Genetics Discord server)

Strawberry, fuel, and cookiesterpenes with a new level of exotic bling make Cherry Cosmo an early star of 2022. Highly regarded breeder Exotic Genetix has folded Cookies upon Cookies in his Baker’s Dozen strain (Milk & Cookies x Rainbow Chip). His Jan. 25 release of Baker’s Dozen crosses includes Cherry Cosmo (Red Pop x Baker’s Dozen), which promises an explosive, cosmic, indica-hybrid space trip.

Exotic Genetix’s breeder Mike (aka “Mr. Stimmy”) has a massive series of indoor grow rooms to experiment—constantly ratcheting up the definition of “Zaza.”

“He throws away plants that other breeders would kill to have in their garden,” said seed seller Luscious Genetics, in a Leafly interview. “That level of discernment is superhuman. He just knows his shit.”

There’s so many phenomenal GSC genetics out there.

See also: Compound Genetics Exotic² (Red Pop x Apples & Bananas); Ethos Genetics’ End Game R2; Seed Junky Genetics’ Jealousy crosses, like Zealousy; or Cookies+Compound Genetics Lemonchello 28 x Jet Fuel Gelato seeds; Wyeast Farms’ line of creamy, sweet, spicy, cinnamon-tinged Horchata crosses; Capulator’s Booty Clapper; and Lovin In Her Eyes’ Spanish Moon S1.

Zkittlez’s hottest progeny

Rainbow Belts 3.0

Archive Seeds Rainbow Belts 3.0 comes out Feb. 1 on Archive Seedbank. (Courtesy Archive Seeds)
Archive Seeds Rainbow Belts 3.0 comes out Feb. 1 on Archive Seedbank. (Courtesy @Archiveseedbank)

Grab some Cup-winning, hyper-giddy, candy-aisle terpenes for ‘22. Breeder Archive Seedbank has mastered the genetics of Rainbow Belts and Moonbow, and thus the future of Zkittlez flavors.

The smell? “Zkittlez plus limey, candied, petroleum-fumed dank,” Archive Seedbank stated in an email announcement.

The effect? Bright, neon flavor meets intense, face-melting, OG power.

“I’m always looking for that sweetness in the strains that I love to smoke,” said Ellen Holland, author of 2021 book “WEED: A Connoisseur’s Guide to Cannabis.” “I really like the zkittlez and that uplifting, bright, bergamot, fruity flavor that it brings to the crosses of zkittlez.”

Archive Seeds breeder Fletch knows the hash heads need resin, too. Rainbow Belts 3.0 seed packs contain “Dry, sandy resin phenotypes that are packed with Gobstopper, Blue Sour Patch, tropical Zkittlez overtones.”

Get your debit card ready. Rainbow Belts 3.0 (Rainbow Belts #20 x Moonbow 112 F2 #60) 12-packs of regular seeds go on sale Feb. 1 at Archive Seedbank and select sellers.

Zazaya

Z3 terps will rule 2022. (Courtesy Terphogz)
Z3 terps drown tastebuds in 2022. (Courtesy Terphogz)

Tropical candy terps get even louder with Terphogz Geneticz cross of Z3 and Papaya—Zazaya. Lip-smacking, Hi-Chew flavor meets high-key glee in this next-level flower designed for hashmakers. Keep a close eye on these influential hash strain designers, as the broader market coasts on their wake, said Luscious Genetics co-owner David.

“Growers are looking at a plant and taking into consideration trichome head size and gland size because extraction is such a large portion of revenue,” he said. “The bigger the trichome, the thicker the stalks—they know it’s going to yield more extract.”

I mean, you stick with the Terphogz when you can. I do, anyways.

Ellen Holland, author, ‘WEED: A Connoisseur’s Guide’

“It’s going to be super-tasty—the smells going to be really intense on those ones—because they have so much more resin,” said Holland. “I mean, you stick with the Terphogz when you can. I do, anyways.”

The Terphogz team backcrossed the original Zkittlez with Hindu Kush to start their Z3 line—which includes Cakez (Z3 x Ice Cream Cake) and Grapefruit Zruntz (Zruntz x Grapefruitz). We’re hearing about feminized Terp Hogz seeds for spring ‘22.

See also: Masonic Seed Company’s Wilmint; Bloom Seeds’ Rainbow Guava; Clearwater Genetics + Tiki Madman project’s Devil Driver; and Swamp Boys Seeds’ Guava Now N Later (Now N Later x White91 x Guava Jelly).

Savory terps of today

Meat Breath crosses

Savory terps have gotten more acrid, funky, weird, and potent in 2022 to counterbalance all the sweet dessert strains. We’re here for it.

The modern savory terp movement has built a home base around GMO Cookies, OGKB, Mendo Breath, and their offspring.

“Anything GMO is going to get gigantic,” said Luscious Genetics.

Thug Pug Genetics breeder “Gromer” comes out of early retirement this winter with Meat Breath crosses, another successor to Peanut Butter Breath. Divisive and unforgettable, this is the modern analog to old-school Cheese or Cat Piss.

“There’s something intriguing about pungent odor, especially if it’s related to an existing bodily musk. We’re drawn to that,” said Luscious Genetics.

Who run the world? Thicc girls: Humboldt Seed Co Garlic Budder (Courtesy Humboldt Seed Co)
Who run the world? Thicc girls: Humboldt Seed Co Garlic Budder (Courtesy Humboldt Seed Company)

Humboldt Seed Co.’s Nat Pennington has come around to pungent garlic terps, he said. “It’s funny because I was resistant at first. Of course, you try GMO and you understand.”

“If you’re in that savory category, that’s gonna be probably stronger and more fuel forward and gassy,” said Holland.

Need more stank? See also: Humboldt Seed Company’s Garlic Budder (GMO x Fortune Cookies); Swamp Boy Seeds’ Maconga (White Uchem x GMO/TK Skunk); Archive Seedbank’s Show Time (NorCal Cat Piss x Dosidos); Rebel Grown’s Double OG Chem S1.

Super stellar sativas

Super Lemon Pupil

Super Lemon Pupil (Courtesy Mass Medical Strains)
Super Lemon Pupil kicks off the #Yearofthehaze (Courtesy Mass Medical Strains)

Enough with the dense, dark, sedative Cookies strains. Give us longer, lighter, brighter sativas, too, in ‘22.

Got a foggy garden? Sativas can be more mold-resistant and far more unique than the next version of Gelato, Holland said. “They don’t have as gigantic of buds and don’t get problems like mold on the inside you can’t even see, or a caterpillar crawling halfway through it.”

“If you’re going to grow it yourself it might be easier to start with something that has a more sativa-leaning profile,” Holland.

Mass Medical Strains is a proud, old-school sativa lover, and has proclaimed 2022 the #yearofthehaze. First in their string of releases: Super Lemon Pupil—a Franco Loja-selected cut of Super Lemon Haze crossed to Mass Medical’s Star Pupil.

Super Lemon Pupil buds get big but stay mold-resistant. (Courtesy Mass Medical Strains)

Lemon, lacquer, European haze, and citrus will perfume your grow room. It’s super zippy—with a very sharp and uplifting profile.

“The power of the Haze mixed with the vibe of the Pupil is simply perfection,” Mass Medical Strains wrote to Leafly. “Effects can border on psychedelic, inspiring new ways of thinking and enhanced perception and awareness.”

Ready for a spirit journey? Mass Medical also touts Thug Pug collaboration Anaphylaxis (PB Breath x Deadly Sativa). “If you are struggling with anxiety or depression this one might be best avoided, it could be tough to handle unless you feel ready for the intensity.”

There’s way more landrace, or legacy, strain work out there. See also: Aww yeah, Hendrx Nursery’s Santa Cruz Blue Dream x Old Dave Skunk; Archive Seedbank’s Island Girl, combining Dosidos to a mix of Malawi, 95’ NL5, Haze F2, Sensi Star, and Molokai Frost; and Masonic Seeds’ Wilson the World landrace uses the hash-dumper strain Wilson to bulk up to Kishkak, Acapulco Gold, Panama Red, or Saipan.

Raspberry Parfait

Here’s a high-yield, farming-friendly, modern sativa for the hash heads. Raspberry Parfait is raspberry and vanilla yogurt-flavored yoga fuel. Humboldt Seed Co.’s unique sativa-dominant cross of Truffula Tree x Shiska Berry bursts with long sesquiterpenes, giving it extra-robust shelf life, and making for phenomenal extracts.

Humboldt Seed Co. did a Raspberry Parfait extract collaboration that they hope will take home an Emerald Cup in 2022. You can take home Raspberry Partfait seeds from California stores.

Starberry Cough

Strawberry Cough x Stardawg is Starberry Cough. (Courtesy Dark Heart Nursery)

Our ‘22 motto is: “Smoke the weed you want to see in the world,” and man, we’ve missed Strawberry Cough.

Major clone seller Dark Heart Nursery agrees. This year they’re bringing out Starberry Cough—a Kyle Kushman-selected cross of the fruity euphoria of Strawberry Cough with the energizing rush of Stardawg.

The cross gives old school Cough some modern bling, terps, and yield, marrying the sweetness of strawberries with the gasoline of Chemdog. Dark Heart Nursery clones are available at licensed California retail stores.


OK—we’re leaving out some legendary breeders and essential new crosses, but we don’t want to overwhelm anyone. Look out for more 2022 Leafly seed guides focused on autoflowers and high-CBD strains, and heck, maybe even pure throwback nostalgia strains. (Anyone got some solid Blue Dream or Urkle cuts? Asking for a friend.)

Get out there and grow the weed you want to smoke in the world!

(Courtesy Humboldt Seed Co)

What strain do you want to grow this year? Leave a nice comment below.

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David Downs
David Downs
Leafly Senior Editor David Downs is the former Cannabis Editor of the San Francisco Chronicle. He's appeared on The Today Show, and written for Scientific American, The New York Times, WIRED, Rolling Stone, The Onion A/V Club, High Times, and many more outlets. He is a 2023 judge for The Emerald Cup, and has covered weed since 2009.
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